Monovisc is a single 4 ml injection of 88 mg of hyaluronic acid, with no steroid. The hyaluronic acid is made by fermentation rather than from animal sources, and it is lightly cross-linked so it stays in the joint for longer. It is made by Anika Therapeutics.
How it works
Hyaluronic acid · tops up the joint’s natural lubrication and cushioning. Relief builds over the first couple of weeks, then can last six months or more.
021326+ weeks
Based on the manufacturer’s data. Everyone responds differently.
Who it may suit
- Mild to moderate osteoarthritis of the knee, hip, shoulder or ankle
- Pain that hasn’t settled with exercise, rehab and simple painkillers
- People who want to avoid or limit steroid injections
Not suitable if you have
- An allergy to hyaluronic acid products
- An infection or skin problem where the injection would go
We check all of this at your assessment.
What happens at Synovia
- Assessment. We examine the joint, review any scans and confirm whether Monovisc is right for you.
- Injection. One injection in clinic, guided by imaging where needed. If the joint is swollen, we may draw off excess fluid first.
- Follow-up. We check how the joint is responding and plan your rehab. A repeat injection after six months has been shown to be safe if you need one.
Possible side effects
Side effects are usually mild and short-lived: some pain, swelling, warmth, redness, bruising or itching around the joint. Infection is rare. Call us straight away if the area becomes hot, red and increasingly painful, or you feel unwell or feverish.
The evidence
In a randomised, double-blind trial of 369 people with knee osteoarthritis, Monovisc improved pain and joint function compared with a saline placebo over 26 weeks, with no serious side effects linked to the product.
US FDA Summary of Safety and Effectiveness Data, P090031.